VIP (5mg)
VIP (Vasoactive Intestinal Peptide) is a 28-amino-acid neuropeptide produced throughout the nervous system, gut, and immune cells, investigated in research for anti-inflammatory effects, vasodilation, and modulation of immune function.
About VIP
Vasoactive Intestinal Peptide (VIP) is a 28-amino-acid neuropeptide widely distributed throughout the nervous system, gastrointestinal tract, lungs, and immune cells. It is a member of the secretin/glucagon peptide family and acts through two receptors, VPAC1 and VPAC2. Research has documented broad effects spanning vascular biology, immune modulation, and inflammation regulation.
Mechanism in Research Literature
Research on VIP has documented:
- Binding to VPAC1 and VPAC2 receptors on diverse cell types
- Smooth muscle relaxation and vasodilation
- Suppression of pro-inflammatory cytokine production
- Promotion of regulatory T-cell (Treg) differentiation
- Modulation of gut-brain axis signaling
- Effects on bronchial smooth muscle and pulmonary function
Research Context
VIP has been investigated in studies exploring:
- Chronic inflammatory response syndrome (CIRS) and biotoxin-related research
- Inflammatory bowel disease research models
- Autoimmune research with Treg-focused mechanisms
- Pulmonary and bronchial research
- Gut-brain axis signaling
Related Research Peptides
VIP appears in literature alongside other immune-modulating research peptides (KPV, Thymosin Alpha-1, LL-37) and broader anti-inflammatory research compounds.
