
TB-500 (10mg)
TB-500 is a synthetic fragment of Thymosin Beta-4, a 43-amino-acid actin-binding protein. Research has explored TB-500’s role in cell migration, vascular remodeling, and tissue regeneration.
About TB-500
TB-500 is a synthetic fragment of Thymosin Beta-4 (Tβ4), a 43-amino-acid protein that is one of the most abundant actin-binding proteins in mammalian cells. Tβ4 is present in virtually every tissue and plays roles in cell migration, blood vessel formation, and tissue repair. TB-500 has been investigated across regenerative medicine literature spanning cardiac, dermal, corneal, and connective tissue research.
Mechanism in Research Literature
Research on TB-500/Tβ4 has documented:
- Binding to and sequestration of G-actin (the monomer form)
- Regulation of actin polymerization dynamics
- Promotion of endothelial and stem cell migration
- Stimulation of angiogenesis in research models
- Anti-inflammatory effects in injury models
- Reduction of scar formation in tissue repair studies
Research Context
TB-500 has been investigated in studies exploring:
- Cardiac tissue regeneration following injury models
- Wound healing including reduced scarring research
- Connective tissue (tendon, ligament) repair
- Corneal regeneration research
- Vascular remodeling and angiogenesis
Related Research Peptides
TB-500 appears in literature alongside other tissue-repair compounds (BPC-157, GHK-Cu, IGF-1 LR3) and as a component of pre-formulated research blends (GLOW 50, KLOW, BPC-157/TB-500 combination).

