Selank (10mg)
Selank is a synthetic seven-amino-acid peptide derived from the natural immunomodulatory peptide tuftsin, investigated in Russian and broader research literature for anxiolytic, cognitive, and immune-modulating activity.
About Selank
Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) designed as a stable analog of the natural tetrapeptide tuftsin. It was developed at the Russian Academy of Sciences Institute of Molecular Genetics. The added C-terminal extension significantly increases stability against enzymatic degradation, supporting longer-duration research applications including intranasal delivery models.
Mechanism in Research Literature
Research on Selank has documented:
- Modulation of GABA neurotransmission in central nervous system models
- Effects on serotonin and dopamine signaling pathways
- Modulation of BDNF (brain-derived neurotrophic factor) expression
- Immune-modulating activity inherited from the tuftsin parent structure
- Effects on enkephalin enzymatic stability in research models
- Anxiolytic effects in animal behavioral research without classical sedation
Research Context
Selank has been investigated in studies exploring:
- Anxiolytic peptide pharmacology distinct from benzodiazepines
- Cognitive function and memory research
- Neuroinflammation and stress-response modulation
- Intranasal peptide delivery research
- Immune modulation via tuftsin-related pathways
Related Research Peptides
Selank appears in literature alongside other Russian-research-program peptides (the Khavinson peptide series including Epithalon and Pinealon), broader neuroactive research compounds (DSIP), and immune-modulating peptides.
