LL-37 (10mg)
LL-37 is a 37-amino-acid cathelicidin antimicrobial peptide produced endogenously by human immune cells and epithelial tissue, investigated extensively in research for innate immune function and antimicrobial activity.
About LL-37
LL-37 is the sole human cathelicidin — a class of antimicrobial peptides central to innate immune defense. It is produced and stored by neutrophils, macrophages, and epithelial cells, and is released upon immune activation. Research has documented broad antimicrobial activity along with immunomodulatory effects beyond direct antimicrobial action.
Mechanism in Research Literature
Research on LL-37 has documented:
- Direct disruption of microbial membranes (bacterial, viral, fungal)
- Activity against biofilms in research models
- Chemoattractant effects on immune cells
- Modulation of cytokine production in inflammatory contexts
- Effects on wound healing and re-epithelialization
- Dose-dependent pro- and anti-inflammatory effects in literature
Research Context
LL-37 has been investigated in studies exploring:
- Innate immune defense and antimicrobial peptide biology
- Biofilm-related infection models
- Chronic infection research including atypical and persistent pathogens
- Wound healing and skin barrier function
- Immunomodulatory effects beyond antimicrobial activity
Related Research Peptides
LL-37 appears in literature alongside other immune-modulating research peptides (Thymosin Alpha-1, KPV, VIP) and broader innate-immunity research compounds.
