CJC without DAC (10mg)
CJC No DAC (Mod GRF 1-29) is a synthetic 29-amino-acid analog of growth hormone-releasing hormone (GHRH) with a short half-life of approximately 30 minutes, investigated in research for pulsatile GH release.
About CJC No DAC
CJC No DAC — also known as Mod GRF 1-29 — is a synthetic analog of the first 29 amino acids of human growth hormone-releasing hormone (GHRH). The "No DAC" designation indicates the absence of the Drug Affinity Complex modification that extends half-life. As a result, CJC No DAC has a short circulating half-life (~30 minutes) and produces a discrete pulse of GH release rather than sustained elevation.
Mechanism in Research Literature
Research on CJC No DAC focuses on its GHRH-receptor agonism:
- Binds to GHRH receptors in the anterior pituitary
- Triggers release of stored growth hormone in a discrete pulse
- Short half-life preserves the body’s pulsatile GH rhythm
- Does not appear to suppress endogenous GHRH signaling at typical research doses
- IGF-1 elevation is modest compared to long-acting GH peptides
Research Context
CJC No DAC has been investigated in studies exploring:
- Pulsatile vs. sustained GH release pharmacology
- GHRH receptor signaling and downstream IGF-1 response
- Combination protocols with ghrelin-receptor agonists (notably Ipamorelin)
- Comparative kinetics vs. CJC-1295 with DAC
Related Research Peptides
CJC No DAC appears in literature most often alongside Ipamorelin (the most-studied combination), as well as Sermorelin, Tesamorelin (other GHRH-pathway peptides), and downstream IGF-1 LR3 research.
For research and educational use only. Not for human consumption. Not intended to diagnose, treat, cure, or prevent any disease.
